Sunday 23 June 2019

Reforming pharmacy benefit manager practices may lead to drug cost savings

Efforts to control health care costs in the United States often focus on the listed prescription drug prices, but a perspective published by the Journal of the American Medical Association suggests that unregulated pharmacy benefit manager practices also may contribute to escalating expenses.

* This article was originally published here

Shaken and stirred: Scientists capture the deformation effect of shock waves on a material

Understanding how shock waves affect structures is crucial for advancements in material science research, including safety protocols and novel surface modifications. Using X-ray diffraction probes, scientists at the Institute of Materials Structure Science of KEK, Tokyo of Tech, Kumamoto University, and University of Tsukuba studied the deformation of polycrystalline aluminum foil when subjected to a laser-driven shock wave.

* This article was originally published here

Robot circulatory system powers possibilities

Untethered robots suffer from a stamina problem. A possible solution: a circulating liquid—"robot blood"—to store energy and power its applications for sophisticated, long-duration tasks.

* This article was originally published here

Multi-mobile (M2) computing system makes Android, iOS apps sharable on multiple devices

Computer scientists at Columbia Engineering have developed a new computing system that enables current, unmodified mobile apps to combine and share multiple devices, including cameras, displays, speakers, microphones, sensors, and GPS, across multiple smartphones and tablets. Called M2, the new system operates across heterogeneous systems, including Android and iOS, combining the functionality of multiple mobile systems into a more powerful one that gives users a seamless experience across the various systems.

* This article was originally published here

A new drug target for chemically induced Parkinson's disease

More than three decades ago, scientists discovered that a chemical found in a synthetic opioid, MPTP, induced the onset of a form of Parkinson's disease. In a new study led by scientists from the School of Veterinary Medicine, researchers found that an enzyme in the body can metabolize compounds formed in the brain from alkaloids present in certain foods and tobacco into MPTP-like chemicals, triggering a neurodegenerative condition in mice.

* This article was originally published here

Ice lithography: Opportunities and challenges in 3-D nanofabrication

Nanotechnology and nanoscience are enabled by nanofabrication. Electron-beam lithography (EBL), which makes patterns down to a few nanometers, is one of the fundamental pillars of nanofabrication. In the past decade, significant progress has been made in electron-beam-based nanofabrication, such as the emerging ice lithography (IL) technology, in which ice thin-films are used as resists and patterned by a focused electron-beam. The entire process of IL nanofabrication is sustainable and streamlined because spin coating and chemical developing steps commonly required for EBL resists are made needless.

* This article was originally published here

This assistive robot is controlled via brain-computer interface

Researchers at the University of Cassino and Southern Lazio, in Italy, have recently developed a cutting-edge architecture that enables the operation of an assistive robot via a P300-based brain computer interface (BCI). This architecture, presented in a paper pre-published on arXiv, could finally allow people with severe motion disabilities to perform manipulation tasks, thus simplifying their lives.

* This article was originally published here

Researchers discover traditional fluid flow observations may miss the big picture

Before and after comparisons don't tell the full story of chemical reactions in flowing fluids, such as those in a chemical reactor, according to a new study from a collaboration based in Japan.

* This article was originally published here

Embryonic microRNA fuels heart cell regeneration, researchers show

By adulthood, the heart is no longer able to replenish injured or diseased cells. As a result, heart disease or an event like a heart attack can be disastrous, leading to massive cell death and permanent declines in function. A new study by scientists at the Lewis Katz School of Medicine at Temple University (LKSOM), however, shows that it may be possible to reverse this damage and restore heart function, even after a severe heart attack.

* This article was originally published here

Marshall Islanders 'sitting ducks' as sea level rises, says president

Marshall Islands President Hilda Heine stressed Friday the need for dramatic climate action and international support to ensure her people are not left as "sitting ducks" when sea levels inevitably rise.

* This article was originally published here

Blue pigment from engineered fungi could help turn the textile industry green

Often, the findings of fundamental scientific research are many steps away from a product that can be immediately brought to the public. But every once in a while, opportunity makes an early appearance.

* This article was originally published here

Pressure difference and vortex flow of blood in heart chambers may signal heart dysfunction

Japanese scientists at Tokyo University of Agriculture and Technology (TUAT), Teikyo University of Science, and Juntendo University have found—in animal studies—a close relationship between vortex flow and pressure differences in the ventricles, or lower chambers, of the heart. The new information could inform the development of new markers for cardiovascular dysfunction that can lead to heart failure.

* This article was originally published here

Keeping children safe in the 'Internet of Things' age

Children need protection when using programmable Internet computing devices—and Lancaster University scientists have drawn up new guidelines to help designers build in safeguards.

* This article was originally published here

Gender-specific differences in the salivary microbiome of caries-active children

At the 97th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 48th Annual Meeting of the American Association for Dental Research (AADR) and the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR),

* This article was originally published here

Applying active inference body perception to a humanoid robot

A key challenge for robotics researchers is developing systems that can interact with humans and their surrounding environment in situations that involve varying degrees of uncertainty. In fact, while humans can continuously learn from their experiences and perceive their body as a whole as they interact with the world, robots do not yet have these capabilities.

* This article was originally published here

Indigenous oral health inequalities begin in childhood: A multi-country study

At the 97th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 48th Annual Meeting of the American Association for Dental Research (AADR) and the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Dandara Haag, University of Adelaide, Australia, gave an oral presentation on "Indigenous Oral Health Inequalities Begin in Childhood: A Multi-country Study." The IADR/AADR/CADR General Session & Exhibition is held at the Vancouver Convention Centre West Building in Vancouver, BC, Canada from June 19-22, 2019.

* This article was originally published here